- Faculty of Medicine - Biomedizinisches Centrum
- Start date
- as soon as possible
- Application deadline
- 31 May 2021
- Remuneration group
- Part time
- 65 %
Tasks and responsibilities
Our research group focusses on the molecular basis of synapse formation in the central nervous system. The successful candidate will employ state-of-the-art experimental approaches to study the development of synapses in wildtype and transgenic mice. The project will be a continuation of previous studies (Handara et al., (2019). The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons. Developmental Biology 445: 54-67; Handara & Kröger (2019) Alternative splicing and the intracellular domain mediate TM-agrin's ability to differentially regulate the density of excitatory and inhibitory synapse-like specializations in developing CNS neurons. Neuroscience 419: 60-71; Karakatsani et al., (2017). Neuronal LRP4 regulates synapse formation in the developing CNS. Development 144, 4604-4615) and will involve transcriptome analysis, high-resolution confocal microscopy, electrophysiology as well as biochemical and molecular biological techniques.
We are seeking a highly-motivated candidate for our international team. The PhD position requires a master´s degree/diploma in life sciences or related disciplines. Prior experiences in molecular and cellular neuroscience, analysis and breeding of transgenic mice as well as interest and basic knowledge in Developmental Neuroscience are advantageous. Excellent communication skills in English (oral and written) are required.The position is funded according to TV-L 65%.
We offer an exciting research topic with high biomedical relevance in a stimulating and interactive scientific environment. The Ludwig-Maximilians-Universität München (LMU) is one of the most renowned Universities in Europe. Our research facility is located on the research campus in Großhadern/Martinsried. The Department of Physiological Genomics is located in the new Biomedical Center of the LMU Munich and offers support and excellent training in a highly stimulatory scientific environment.
This is a part-time job
People with disabilities who are equally as qualified as other applicants will receive preferential treatment.
More informations find here.
Applications should be sent by email to:
Department of Physiological Genomics
Prof. Dr. Stephan Kröger
Großhaderner Str. 9
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