PhD position (m/f/x) available in Developmental Neuroscience

Institution
Faculty of Medicine - Biomedizinisches Centrum
Start date
as soon as possible
Application deadline
31 May 2021
Remuneration group
TV-L
Part time
65 %

Tasks and responsibilities

Our research group focusses on the molecular basis of synapse formation in the central nervous system. The successful candidate will employ state-of-the-art experimental approaches to study the development of synapses in wildtype and transgenic mice. The project will be a continuation of previous studies (Handara et al., (2019). The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons. Developmental Biology 445: 54-67; Handara & Kröger (2019) Alternative splicing and the intracellular domain mediate TM-agrin's ability to differentially regulate the density of excitatory and inhibitory synapse-like specializations in developing CNS neurons. Neuroscience 419: 60-71; Karakatsani et al., (2017). Neuronal LRP4 regulates synapse formation in the developing CNS. Development 144, 4604-4615) and will involve transcriptome analysis, high-resolution confocal microscopy, electrophysiology as well as biochemical and molecular biological techniques.

Requirements

We are seeking a highly-motivated candidate for our international team. The PhD position requires a master´s degree/diploma in life sciences or related disciplines. Prior experiences in molecular and cellular neuroscience, analysis and breeding of transgenic mice as well as interest and basic knowledge in Developmental Neuroscience are advantageous. Excellent communication skills in English (oral and written) are required.The position is funded according to TV-L 65%.

Benefits

We offer an exciting research topic with high biomedical relevance in a stimulating and interactive scientific environment. The Ludwig-Maximilians-Universität München (LMU) is one of the most renowned Universities in Europe. Our research facility is located on the research campus in Großhadern/Martinsried. The Department of Physiological Genomics is located in the new Biomedical Center of the LMU Munich and offers support and excellent training in a highly stimulatory scientific environment.

This is a part-time job

People with disabilities who are equally as qualified as other applicants will receive preferential treatment.

Contact

More informations find here.

Applications should be sent by email to:

Biomedical Center
Department of Physiological Genomics
Prof. Dr. Stephan Kröger
Großhaderner Str. 9
82152 Planegg-Martinsried

Email: skroeger@lmu.de

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