- Faculty of Medicine - Walter Brendel Center - Schraml lab at the Biomedical Center
- Start date
- Position available from fall 2021
- Application deadline
- 30 Oct 2021
Allergic diseases often develop in early life and the incidence of childhood allergies continues to rise. DCs are key activators of T cells that critically determine the outcome of allergen encounter. In early life, DCs exhibit qualitative differences compared to adult life, including an intrinsic bias to stimulate type II immunity, which promotes allergic responses. However, the signals that regulate DC function with age remain poorly defined. The current project is integrated into the Forschergruppe (FOR) 2599 and investigates the influence of cytokine signals and early life microbial encounter on the ability of DCs to shape type II immune responses in barrier organs with age.
Tasks and responsibilities
The applicant will use high dimensional single cell technology (flow cytometry and transcriptomics) and DC lineage specific knock out mice of cytokine signalling to gain mechanistic insights into the regulation of DC function with age.
- Commitment and initiative in a dynamic and international research environment
- A team player
- Proficiency in German and English is required
- Expertise in flow cytometry, transcriptomics and/or working with mice is a plus- Applicants should hold a Master’s degree in Immunology, Cell Biology, Biomedicine, Bioinformatics or the like.
- An enthusiastic international team
- Offers to support compatibility of family and work
- A diverse range of tasks associated with a high degree of responsibility
- Position available from fall 2021, salary based on German public service scale (TV-L), full-time employment.
Also possible in a part-time capacity.
People with disabilities who are equally as qualified as other applicants will receive preferential treatment.
Quote ”P22” with enquiries/applications directly to Dr. Barbara Schraml. Please include merged in a single pdf file: a short statement of research interests and why you chose to apply for this position, CV, list of publications, names and contact information of two references.
For more information visit: https://www.schraml-lab.de/
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