30 Nov

Gene Silencing in HSPCs with an Apolipoprotein A1-Based Nanodelivery Platform

Opening hours / Beginning:

5:15 pm

30 November 2023


ICEM Building at LMU Würmtalstr. 201 81375 München

© cas

Speaker: Prof. Roy van der Meel, Ph.D.
Moderation: Dr. Sabine Schneider (LMU)

Nucleic acid therapeutics are revolutionizing healthcare via gene inhibition, addition, replacement or editing. Lipid nanoparticle (LNP) technology is the current gold standard platform that enabled the clinical translation of the first siRNA drug Onpattro and the COVID-19 mRNA vaccines. Nevertheless, current LNP systems are mostly suited for vaccine purposes following local administration or hepatic delivery following intravenous administration. To unleash RNA’s full therapeutic potential, Roy van der Meel introduces modular nanoplatform technology for systemic nucleic acid delivery to immune cells in hematopoietic organs using apolipoproteins.

Roy van der Meel is Professor of Precision Medicine at the Department of Biomedical Engineering, Eindhoven University of Technology.

Registration is required for participation. Further information you can find on this website.

The Center for Advanced Studies at LMU provides a forum for scientific exchange and discussion that bridges the divide between the established disciplines. Its activities are designed to promote all forms of collaborative research and to stimulate interdisciplinary communication within the University. In addition, it facilitates the integration of visiting scholars and scientists into the academic life of the University.

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