Neuroscience: Graded remapping of hippocampal place cells

16 Sept 2021

LMU neuroscientist Dustin Fetterhoff reports in the journal Cell Reports

The hippocampus is a part of the brain that plays a major role in spatial navigation. It enables us to navigate through the world and remember how events and locations are interrelated. Hippocampal neurons, named “place cells,” thereby mostly encode spatial position. Together, these cells build up a neuronal map of our surroundings, which enables us to distinguish one location from another.

LMU neuroscientists led by Dustin Fetterhoff and Christian Leibold have now shown that hippocampal place cells cooperatively adjust their firing patterns after receiving altered visual information at a known location. The scientists defined this continuous alteration in the population as “graded remapping.”

Dustin Fetterhoff, Andrey Sobolev, Christian Leibold: Graded remapping of hippocampal ensembles under sensory conflicts. Cell Reports 2021

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