Animal welfare in translational research

From the lab to clinical practice: The goal is to translate new therapies into clinical use as quickly as possible. In human medicine, pigs – along with other animal species – are frequently used at LMU and the University Hospital because they resemble humans in key physiological and anatomical aspects. Veterinary research, by contrast, can focus directly on the target species for a given treatment or product, such as the development of innovative pet food for dogs and cats.

Real-world examples

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Multiple sclerosis: Triggers in the gut flora
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Transition from basic research to translational research

Clinical Neuroimmunology

A twin study has identified bacteria in the small intestine that play a role in the development of MS. The study was conducted by a large team from several research institutions led by Dr. Anneli Peters (LMU Biomedical Center) and Professor Hartmut Wekerle (Max Planck Institute for Biological Intelligence).

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Opening of ICON research center: concentrated expertise for medical research transfer
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Translation

Research center for medical science transfer

The newly opened Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICON) brings together interdisciplinary research on diseases of the cardiovascular system and translates innovative therapeutic approaches into clinical practice.

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Concentrated expertise for medical research transfer
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Professor Steffen Massberg, Director of the Department of Cardiology at LMU University Hospital, and Eckhard Wolf, Professor of Molecular Animal Breeding and Biotechnology at LMU, discuss the possibilities and goals of ICON.

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Pigs as potential organ donors for humans
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Pigs as model organisms

Pigs are used as model organisms for studying diseases, and they could also become organ donors for humans. A visit to LMU’s Center for Innovative Medical Models (CiMM), where research is conducted on these animals.

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Animal welfare: reducing lab experiments on primates
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EU Collaborative Project: Innovative Health Initiative “NHPig”

A new EU collaborative project, the Innovative Health Initiative “NHPig,” aims to improve efficiency and animal welfare in medical safety research. An interview with research project coordinator Eckhard Wolf of LMU

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Cancer treatment: optimization of CAR T-cell therapy
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Immunopharmacology

The team led by LMU physician Professor Sebastian Kobold at the University Hospital has found a way to direct the body's own immune system to destroy solid tumors.

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Tuberculosis research: promising new active agent
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Infectious diseases and Tropical Medicine

The effectiveness of the new antibiotic BTZ-043 has been demonstrated by, among others, researchers at the Tropical Medicine Institute of the University Hospital led by Professor Michael Hoelscher, director of the Institute for Infectious and Tropical Medicine at LMU.

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Curing eye diseases with gene therapy
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Gene therapy for retinal diseases

A new DFG research group led by LMU Professor Stylianos Michalakis at the LMU Eye Clinic is developing innovative approaches for the treatment of retinal diseases.

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